Prep: Preheat oven to 375°F. Line baking sheet with parchment.
Cook Filling: Brown beef and onions. Add garlic, Worcestershire sauce, salt and pepper. Drain excess fat and cool.
Assemble: Flatten each biscuit into a 4-inch circle. Add 1½ tbsp beef mixture and 2-3 cheese quarters to center.
Seal: Gather edges and pinch firmly to seal completely. Roll into balls.
Season: Mix melted butter with Parmesan, garlic powder, and Italian seasoning. Brush over dough balls.
Bake: Place bombs seam-side down. Bake 14-16 minutes until golden brown.
Serve: Let cool 3-5 minutes before serving.